Package: bioIOT Type: Package Title: Inverse Optimal Transport for Single-Cell Trajectory Analysis Version: 0.2.1 Authors@R: person(given = "Han", family = "Dong", role = c("aut", "cre"), email = "dh411424@163.com", comment = c(Nickname = "XTSgreen")) Description: Semi-relaxed inverse optimal transport ('IOT') for single-cell state-transition and 'pseudotime' analysis: a self-contained R solver (Anderson-accelerated soft 'Sinkhorn' with exact implicit gradients), feature-weight fitting with a two-stage bias-corrected refit and multi-restart, state transition matrices, random-walk 'pseudotime', 'ggplot2' visualisation, soft-gated Seurat and 'SingleCellExperiment' interfaces, reproducible simulated demo data, and bulk-cohort pathway scoring utilities. License: MIT + file LICENSE Encoding: UTF-8 Depends: R (>= 4.0.0) Imports: utils, ggplot2 Suggests: testthat (>= 3.0.0), knitr, rmarkdown, SingleCellExperiment, Seurat, SummarizedExperiment, S4Vectors URL: https://github.com/XTSgreen/bioIOT-R BugReports: https://github.com/XTSgreen/bioIOT-R/issues VignetteBuilder: knitr Config/testthat/edition: 3 Repository: https://xtsgreen.r-universe.dev Date/Publication: 2026-09-04 14:11:25 UTC RemoteUrl: https://github.com/xtsgreen/bioiot-r RemoteRef: HEAD RemoteSha: 1efea6cda88a03941a985b8b17002432323a57d3 NeedsCompilation: no Packaged: 2026-09-25 09:56:53 UTC; root Author: Han Dong [aut, cre] (Nickname: XTSgreen) Maintainer: Han Dong